Therapy

Severe Aortic Valve Stenosis

Severe Aortic Stenosis is a narrowing of the aortic valve opening. This narrowing keeps the valve from opening fully, reducing blood flow to the body and making the heart work harder.

Symptoms of Aortic Stenosis include:

  • Chest pain
  • Dizziness
  • Fatigue
  • Out of breath
  • Irregular heartbeat

Causes of Aortic Stenosis include:

  • Age
  • Calcium buildup
  • Infection of the heart
  • Failing aortic surgical valve

Severe Aortic Stenosis Treatment

Severe Aortic Stenosis Treatment include:

  • Surgical Aortic Valve Replacement (SAVR) - heart surgery where the diseased valve is removed and replaced
  • Transcatheter Aortic Valve Replacement (TAVR) - catheter-based procedure where a replacement valve is fed through to the valve site, often through an insertion point in the thigh

Latest trends in treating Aortic Stenosis

Since the minimally invasive transcatheter aortic valve replacement (TAVR) surgery became the standard of care for patients with aortic stenosis in 2017, the aortic valve replacement market has seen growth by 20% year-over-year.

This increase is due to both the growing incidence of aortic stenosis and the increased occurrence of aortic valve replacement in younger patients. While valve replacement surgery was once only considered for high-risk elderly patients, it is now recognized that TAVR is a procedure with reasonable risk for better health outcomes. The valve replacement market is seeing more growth as the medical field shifts to earlier intervention, prompting younger patients to consider the procedure.

Lancalotti et al;
Courtesy of Windecker S. TCT 2019
Barbanti et al; J AM HeartAssoc 2018
*Popma FF, et al. Transcatheter aortic-valve replacement with a self-expanding valve in low-risk patients. N Engl J Med. 2019;380(18):1706-1715.
*Mack, MJ, et al. Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients. N Engl J Med. 2019;380(18):1695-1705

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Durability is now a critical issue

With younger patients receiving heart valves, durability is now a critical issue.

We bring innovation to the cardiovascular surgery space through our revolutionary tissue proven to last over 10 years in the human body. The inspiration for our DurAVR™ heart valves* stemmed from multiple conversations with interventional cardiologists, who reiterated that valve durability and repeat replacements were posing a large risk to patient health.

The proven benefits of our ADAPT® tissue paired with the unique design of our 3D single piece aortic valve, answers the durability equation, and provides a much-needed solution to the challenges facing heart surgeons today.

Learn more about ADAPT® technology

Learn more about DurAVR™ - 3D Single Piece Aortic Valve*

Data on File
[1]: 2014 AHA/ACC guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.

Reproduction of this material in any form without the permission of the Company is prohibited